TABLE OF CONTENTS 1) INTRODUCTION; 2) ETHNOBOTANICAL INFORMATION OF NORTH EAST Arunachal Pradesh Assam; Nagaland; Mizoram; Tripura; Manipur; Meghalaya; 3) SIGNIFICANCE OF TRADITIONAL MEDICINES; North east; Traditional medicines and significance in Africa countries; Traditional medicines in developed countries; Traditional medicines and maintenance of health care live stock; The industrial use of traditional medicines; 4) PROBLEMS OF TRADITIONAL MEDICINES Problem of traditional medicine in north east. 5) COMMERCIAL USE OF TRADITIONAL MEDICINES; North east; The global and national market sale for herbal medicines; Emerging economic benefit; 6) National AND INTERNATIONAL ATTEMPTS TO PROTECT TRADITIONAL MEDICINES; International; Law made by many countries for protection of traditional Medicines Conservation of medicinal plants; Database; North east. 7) INTELLECTUAL PROPERTY RIGHTS AND TRADITIONAL KNOWLEDGE; Patent protection; Trade secret.; 8) SUI GENERIS SYSTEM; Some of the noteworthy sui generis developed by the various Countries for the protection of indigenous knowledge 9) CONCLUSION AND SUGGESTIONS; 10) BIBLIOGRAPHY